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Medications know to cause bone marrow suppression (e.g., myelosuppressive antineoplastic agents) may result in a blunted or impeded response to methylcobalamin, vitamin B12 therapy

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For example, low iron levels may cause fatigue or shortness of breath while low vitamin D levels may cause bone pain or mood changes

Severe B-12 Deficiency Can Be Missed May 03, 2022 B-12 deficiency can cause severe symptoms, even when B-12 levels in the blood are not low, as shown in a recent case

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However, individuals can take steps to maximize the effectiveness of B12 injections, including maintaining a balanced diet, staying hydrated, addressing underlying health conditions, following healthcare provider recommendations, and adopting a healthy lifestyle